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Piezoresistive pressure sensor with high sensitivity for medical application using peninsula-island structure

Tingzhong XU, Hongyan WANG, Yong XIA, Zhiming ZHAO, Mimi HUANG, Jiuhong WANG, Libo ZHAO, Yulong ZHAO, Zhuangde JIANG

Frontiers of Mechanical Engineering 2017, Volume 12, Issue 4,   Pages 546-553 doi: 10.1007/s11465-017-0447-9

Abstract: Moreover, the influence of the installation angle on the sensing chip output was analyzed, and an applicationTherefore, the proposed pressure sensor has strong potential for medical equipment application.

Keywords： MEMS     low pressure sensor     peninsula-island     ultra-high sensitivity     medical application    

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Application of StrucGP in medical immunology: site-specific -glycoproteomic analysis of macrophages

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 304-316 doi: 10.1007/s11684-022-0964-8

Abstract: The structure of N-glycans on specific proteins can regulate innate and adaptive immunity via sensing environmental signals. Meanwhile, the structural diversity of N-glycans poses analytical challenges that limit the exploration of specific glycosylation functions. In this work, we used THP-1-derived macrophages as examples to show the vast potential of a N-glycan structural interpretation tool StrucGP in N-glycoproteomic analysis. The intact glycopeptides of macrophages were enriched and analyzed using mass spectrometry (MS)-based glycoproteomic approaches, followed by the large-scale mapping of site-specific glycan structures via StrucGP. Results revealed that bisected GlcNAc, core fucosylated, and sialylated glycans (e.g., HexNAc4Hex5Fuc1Neu5Ac1, N4H5F1S1) were increased in M1 and M2 macrophages, especially in the latter. The findings indicated that these structures may be closely related to macrophage polarization. In addition, a high level of glycosylated PD-L1 was observed in M1 macrophages, and the LacNAc moiety was detected at Asn-192 and Asn-200 of PD-L1, and Asn-200 contained Lewis epitopes. The precision structural interpretation of site-specific glycans and subsequent intervention of target glycoproteins and related glycosyltransferases are of great value for the development of new diagnostic and therapeutic approaches for different diseases.

Keywords： macrophage     glycoproteome     glycopeptides     N-glycan structures     PD-L1    

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Application of artificial intelligence in surgery

Xiao-Yun Zhou, Yao Guo, Mali Shen, Guang-Zhong Yang

Frontiers of Medicine 2020, Volume 14, Issue 4,   Pages 417-430 doi: 10.1007/s11684-020-0770-0

Abstract: Artificial intelligence (AI) is gradually changing the practice of surgery with technological advancements in imaging, navigation, and robotic intervention. In this article, we review the recent successful and influential applications of AI in surgery from preoperative planning and intraoperative guidance to its integration into surgical robots. We conclude this review by summarizing the current state, emerging trends, and major challenges in the future development of AI in surgery.

Keywords： artificial intelligence     surgical autonomy     medical robotics     deep learning    

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A literature review of perishable medical resource management

Frontiers of Engineering Management   Pages 710-726 doi: 10.1007/s42524-023-0278-9

Abstract: healthcare providers have faced mounting pressure to effectively manage highly perishable and limited medical

Keywords： perishable medical resources     organ transplant     healthcare products     decision analytics     operations management    

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Effectiveness of preventive medicine education and its determinants among medical students in Malaysia

Shirin Anil,Mohamed Shukry Zawahir,Redhwan Ahmed Al-Naggar

Frontiers of Medicine 2016, Volume 10, Issue 1,   Pages 91-100 doi: 10.1007/s11684-016-0428-0

Abstract:

Preventive medicine has been incorporated in the medical school curriculum, but its effectivenessimportance to learn, and the ability to practice preventive medicine as well as its determinants among the medicalsectional study was conducted through an anonymous online survey among 387 randomly selected final year medicalstudents of four large public medical schools in Malaysia from March to September 2014.” In univariable analysis, being a female, medical school, family size, and perception about the

Keywords： preventive medicine     medical school     medical students    

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Attitude toward preventive counseling and healthy practices among medical students at a Colombian university

Luz Helena Alba,Nora Badoui,Fabián Gil

Frontiers of Medicine 2015, Volume 9, Issue 2,   Pages 251-259 doi: 10.1007/s11684-015-0393-z

Abstract:

Unhealthy behaviors of medical students influence their attitudes toward preventive counseling.The objective of this study was to describe the effect of medical training on the risk profiles and attitudesof medical students toward preventive counseling in a Colombian university.

Keywords： lifestyle     medical students     preventive medicine     counseling     universities     schools     medical    

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Advances in Medical Applications of Additive Manufacturing Review

Chunxu Li, Dario Pisignano, Yu Zhao, Jiajia Xue

Engineering 2020, Volume 6, Issue 11,   Pages 1222-1231 doi: 10.1016/j.eng.2020.02.018

Abstract: cost-effective and versatile technique for the fabrication of geometrically complex objects in the medicalIn this review, we discuss current advances of AM in medical applications for the generation of pharmaceuticals, medical implants, and medical devices.In addition, medical devices used for diagnostics and treatment of various pathological conditions haveThe growing body of research on AM reveals its great potential in medical applications.

Keywords： Additive manufacturing     Medical applications     Pharmaceutics Medical implants     Medical devices    

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Methodological challenges to human medical study

Yixin Zhong,Baoyan Liu,Hua Qu,Qi Xie

Frontiers of Medicine 2014, Volume 8, Issue 3,   Pages 328-336 doi: 10.1007/s11684-014-0359-6

Abstract:

With the transformation of modern medicinal pattern, medical studies are confronted with methodological

Keywords： medical paradigm     traditional Chinese medicine     western medicine     scientific view     scientific methodology    

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Primary health care for all by 2020: The systematic reform of the medical and health system in China

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 3-7 doi: 10.1007/s11684-010-0024-7

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Thanks to all medical workers fighting against COVID-19

Xiao-ping Chen

Frontiers of Medicine 2020, Volume 14, Issue 2,   Pages 249-250 doi: 10.1007/s11684-020-0789-2

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Therapeutic effect of medical glue combined with the great omentum in severe tunica muscularis injury

REN Peitu, LU Baochun, RUAN Xinxian, CHEN Zhiliang, MA Yuliang, FU Hong

Frontiers of Medicine 2008, Volume 2, Issue 2,   Pages 143-146 doi: 10.1007/s11684-008-0027-9

Abstract: The patients with severe tunica muscularis injury were treated by medical glue combined with the greaterTherefore, reasonable use of medical glue combined with the greater omentum can not only improve the

Keywords： abscess     initial     muscularis     anastomotic     medical    

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Survey on deep learning for pulmonary medical imaging

Jiechao Ma, Yang Song, Xi Tian, Yiting Hua, Rongguo Zhang, Jianlin Wu

Frontiers of Medicine 2020, Volume 14, Issue 4,   Pages 450-469 doi: 10.1007/s11684-019-0726-4

Abstract: With medical imaging becoming an important part of disease screening and diagnosis, deep learning-basedapproaches have emerged as powerful techniques in medical image areas.Deep learning has been widely applied in medical imaging for improved image analysis.to pulmonary medical images, datasets, and benchmarks.Lastly, the application of deep learning techniques to the medical image and an analysis of their future

Keywords： deep learning     neural networks     pulmonary medical image     survey    

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Ingestible wireless capsules for enhanced diagnostic inspection of gastrointestinal tract

Mahdi RASOULI, Andy Prima KENCANA, Van An HUYNH, Eng Kiat TING, Joshua Chong Yue LAI, Kai Juan WONG, Su Lim TAN, Soo Jay PHEE

Frontiers of Mechanical Engineering 2011, Volume 6, Issue 1,   Pages 40-44 doi: 10.1007/s11465-011-0204-4

Abstract:

Wireless capsule endoscopy has become a common procedure for diagnostic inspection of gastrointestinal tract. This method offers a less-invasive alternative to traditional endoscopy by eliminating uncomfortable procedures of the traditional endoscopy. Moreover, it provides the opportunity for exploring inaccessible areas of the small intestine. Current capsule endoscopes, however, move by peristalsis and are not capable of detailed and on-demand inspection of desired locations. Here, we propose and develop two wireless endoscopes with maneuverable vision systems to enhance diagnosis of gastrointestinal disorders. The vision systems in these capsules are equipped with mechanical actuators to adjust the position of the camera. This may help to cover larger areas of the digestive tract and investigate desired locations. The preliminary experimental results showed that the developed platform could successfully communicate with the external control unit via human body and adjust the position of camera to limited degrees.

Keywords： wireless capsule endoscopy     ingestible medical device     in-body medical device     miniature actuator     medicalrobot     medical imaging    

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Power sources and electrical recharging strategies for implantable medical devices

WEI Xiaojuan, LIU Jing

Frontiers in Energy 2008, Volume 2, Issue 1,   Pages 1-13 doi: 10.1007/s11708-008-0016-3

Abstract: Implantable medical devices (IMDs) are critically requested for the survival of patients subject to certainAppropriate working of an active implantable medical device (IMD) heavily relies on the continuous supply

Keywords： generation     bio-fuel     ultrasonic     piezoelectric     conventional    

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Effect of the new maternity insurance scheme on medical expenditures for caesarean delivery in Wuxi,

Chun Chen,Zhihong Cheng,Ping Jiang,Mei Sun,Qi Zhang,Jun Lv

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 473-480 doi: 10.1007/s11684-016-0479-

Abstract:

Aiming to control rising medical expenditures and help improve China’s healthcare systems, thisstudy examined whether a cap-based medical insurance scheme with shared financial interest between theWe also used paired sample t-tests and linear regression models to compare the mean medicalAfter the scheme’s implementation, medical expenditures for caesarean deliveries declined and themedical expenditures of women covered by the scheme were significantly lower than those of uninsured

Keywords： maternity insurance scheme     financial incentive     caesarean delivery     medical expenditure     China    

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Title Author Date Type Operation

Piezoresistive pressure sensor with high sensitivity for medical application using peninsula-island structure

Tingzhong XU, Hongyan WANG, Yong XIA, Zhiming ZHAO, Mimi HUANG, Jiuhong WANG, Libo ZHAO, Yulong ZHAO, Zhuangde JIANG

Journal Article

Application of StrucGP in medical immunology: site-specific -glycoproteomic analysis of macrophages

Journal Article

Application of artificial intelligence in surgery

Xiao-Yun Zhou, Yao Guo, Mali Shen, Guang-Zhong Yang

Journal Article

A literature review of perishable medical resource management

Journal Article

Effectiveness of preventive medicine education and its determinants among medical students in Malaysia

Shirin Anil,Mohamed Shukry Zawahir,Redhwan Ahmed Al-Naggar

Journal Article

Attitude toward preventive counseling and healthy practices among medical students at a Colombian university

Luz Helena Alba,Nora Badoui,Fabián Gil

Journal Article

Advances in Medical Applications of Additive Manufacturing

Chunxu Li, Dario Pisignano, Yu Zhao, Jiajia Xue

Journal Article

Methodological challenges to human medical study

Yixin Zhong,Baoyan Liu,Hua Qu,Qi Xie

Journal Article

Primary health care for all by 2020: The systematic reform of the medical and health system in China

Journal Article

Thanks to all medical workers fighting against COVID-19

Xiao-ping Chen

Journal Article

Therapeutic effect of medical glue combined with the great omentum in severe tunica muscularis injury

REN Peitu, LU Baochun, RUAN Xinxian, CHEN Zhiliang, MA Yuliang, FU Hong

Journal Article

Survey on deep learning for pulmonary medical imaging

Jiechao Ma, Yang Song, Xi Tian, Yiting Hua, Rongguo Zhang, Jianlin Wu

Journal Article

Ingestible wireless capsules for enhanced diagnostic inspection of gastrointestinal tract

Mahdi RASOULI, Andy Prima KENCANA, Van An HUYNH, Eng Kiat TING, Joshua Chong Yue LAI, Kai Juan WONG, Su Lim TAN, Soo Jay PHEE

Journal Article

Power sources and electrical recharging strategies for implantable medical devices

WEI Xiaojuan, LIU Jing

Journal Article

Effect of the new maternity insurance scheme on medical expenditures for caesarean delivery in Wuxi,

Chun Chen,Zhihong Cheng,Ping Jiang,Mei Sun,Qi Zhang,Jun Lv

Journal Article